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Resveratrol may support bone health in obese men

September 8, 2015

A new study from Denmark reports that resveratrol seems to increase bone formation and/or mineralization in obese men.

The randomized controlled trial measured changes in bone mineral density (BMD), bone geometry and bone turnover markers (bone alkaline phosphatase) in 66 middle-aged obese men who received a daily 1.000 mg resveratrol, 150 mg resveratrol or placebo for 16 weeks (1). The study results showed that participants who received the high resveratrol dose had a greater increased activity of bone-forming cells and lumbar spine bone mineral density, than participants taking the lower dose or placebo.

The researchers commented that obesity is associated with low-grade inflammation, which may harmfully affect bone health. As resveratrol possesses anti-inflammatory properties, it may have bone protective effects. Future studies of longer duration comprising populations at risk of osteoporosis are needed to confirm these results, the scientists said. Resveratrol is a powerful polyphenol that can be found as compound in grapes and red wine. It has been suggested that resveratrol may also support heart health, blood sugar management and energy endurance enhancement.

References

  1. Ornstrup M. J. et al. Resveratrol Increases Bone Mineral Density and Bone Alkaline Phosphatase in Obese Men: A Randomized Placebo-Controlled Trial. The Journal of Clinical Endocrinology & Metabolism. Published online October 2014.