Topic of the Month
Antioxidants in the Prevention of Cardiovascular Disease – Part 2: Intervention Studies
1 June 2011
Observations from epidemiological studies on the protective effect of antioxidant micronutrients in relation to cardiovascular diseases (see Part 1) warranted an attempt to prove the hypothesis by means of intervention studies. However, the results of many randomized controlled studies were disappointing: many investigations revealed few, if any, differences between groups receiving placebo and those receiving food supplements with vitamin C and/or E and beta-carotene in regard to the risk of developing cardiovascular disease, a benefit was found in only a few groups.