18 November 2010
A combined supplementation of vitamin D and calcium is effective in increasing the bone mineral density of post-menopausal women, even when calcium intakes are adequate, says a new Finnish study.
In the randomized controlled trial, 593 post-menopausal women were randomly selected for bone mineral density (BMD) measurements, with half of the women receiving daily vitamin D (800 IU) plus calcium (1 gram) supplements for three years, while the other group received placebo (1). The results showed that the total body BMD increased significantly more in the group who received supplementation compared with women who received no intervention. Moreover, women who most fully participated in the supplementation study, taking at least 80 percent of the supplements, showed the greatest benefits. The researchers commented that daily vitamin D and calcium supplementation has a positive effect on the skeleton in postmenopausal women, even in those with adequate nutritional calcium intake.
Earlier, a Danish meta-analysis of seven randomized controlled trials with 68,517 people (mean age 69.9 years) from the US and Europe found that the vitamin-mineral combination significantly reduced fractures by 8 percent, and hip fractures by 16 percent (2). Supplemental vitamin D on its own in daily doses equivalent to 10 to 20 micrograms had no effects on fracture prevention. The researchers concluded that daily supplements which combine vitamin D and calcium may reduce the risk of fractures for everyone, regardless of age or gender. However, results from another trial did not back up the positive effect of lowering the risk of fractures (3).
The combination of vitamin D and calcium is recommended to reduce the risk of bone fracture for older people, particularly those at risk of or suffering from osteoporosis. The action of the nutrients is complimentary, with calcium supporting bone formation and repair, while vitamin D helps the body absorb calcium. In 2008, the European Food Safety Authority (EFSA) accepted a health claim linking calcium and vitamin D to bone health in older women.
1 July 2013
A new genetic study from the UK reports that there is a clear causal link between low blood concentrations of vitamin D and the development of hypertension.
1 October 2011
According to a new Australian review, zinc plays a critical role in the regulation of DNA repair mechanisms, cell proliferation, differentiation and cell death.
1 November 2009
“The headline ‘The dark side of vitamin C’ recently appeared in the German newspaper service ‘Die Welt online,’ prompted by an American study showing that artificial antioxidants (N-acetyl cysteine and Trolox) support the metabolism of tumor cells that have become detached from the tumor and could thus promote metastasis.”
