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      Vitamin B5 // Pantothenic Acid

      References

      REFERENCES

      1. Trumbo PR. Pantothenic acid. In: Shils ME, Shike M, Ross AC, Caballero B, Cousins RJ, eds. Modern Nutrition in Health and Disease. 10th ed. Philadelphia: Lippincott Williams & Wilkins; 2006:462–469.
      2. Tahiliani AG, Beinlich CJ. Pantothenic acid in health and disease. Vitam Horm. 1991; 46:165–228.
      3. Brody T. Nutritional Biochemistry. 2nd ed. San Diego: Academic Press; 1999.
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      5. Bender DA. Optimum nutrition: thiamin, biotin and pantothenate. Proc Nutr Soc. 1999; 58(2):427–433.
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      7. Vaxman F, Olender S, Lambert A, et al. Effect of pantothenic acid and ascorbic acid supplementation on human skin wound healing process. A double-blind, prospective and randomized trial. Eur Surg Res. 1995; 27(3):158–166.
      8. Gaddi A, Descovich GC, Noseda G, et al. Controlled evaluation of pantethine, a natural hypolipidemic compound, in patients with different forms of hyperlipoproteinemia. Atherosclerosis. 1984; 50(1):73–83.
      9. Coronel F, Tornero F, Torrente J, et al. Treatment of hyperlipemia in diabetic patients on dialysis with a physiological substance. Am J Nephrol. 1991; 11(1):32–36.
      10. General Practitioner Research Group. Calcium pantothenate in arthritic conditions. A report from the General Practitioner Research Group. Practitioner. 1980; 224(1340):208–211
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      12. Food and Nutrition Board, Institute of Medicine. Pantothenic acid. Dietary Reference Intakes: Thiamin, Riboflavin, Niacin, Vitamin B-6, Vitamin B-12, Pantothenic Acid, Biotin, and Choline. Washington, D.C.: National Academy Press; 1998:357–373.
      13. European Food Safety Authority, Scientific Committee on Food. Tolerable Upper Intake Levels for Vitamins and Minerals. 2006: ISBN: 92-9199-014-0.
      14. Hodges RE, Ohlson MA, Bean WB. Pantothenic acid deficiency in man. J Clin Invest. 1958; 37:1642–1657.
      15. Fry PC, Fox HM, Tao HG. Metabolic response to a pantothenic acid deficient diet in humans. J Nutr Sci Vitaminol (Tokyo). 1976; 22(4):339–346.
      16. Said HM, Ortiz A, McCloud E, Dyer D, Moyer MP, Rubin S. Biotin uptake by human colonic epithelial NCM460 cells: a carrier-mediated process shared with pantothenic acid. Am J Physiol. 1998; 275(5 Pt 1):C1365–1371.
      17. Flodin N. Pharmacology of micronutrients. New York: Alan R. Liss, Inc.; 1988.
      18. Debourdeau PM, Djezzar S, Estival JL, Zammit CM, Richard RC, Castot AC. Life-threatening eosinophilic pleuropericardial effusion related to vitamins B5 and H. Ann Pharmacother. 2001; 35(4):424–426.
      19. Hendler SS, Rorvik DR, eds. PDR for Nutritional Supplements. Montvale: Medical Economics Company, Inc; 2001.
      20. Zempleni J, Suttie JW, Gregory III JF, Stover PJ, editors. Handbook of Vitamins. Fifth Edition, CRC Press: Taylor & Francis Group; 2014.
      21. Linus Pauling Institute – Micronutrient information center. May 2017 accessed.  http://lpi.oregonstate.edu/mic/vitamins/pantothenic-acid#sources.
      22. Leung LH. Systemic lupus erythematosus: a combined deficiency disease. Med Hypotheses 2004; 62(6):922-4.
      23. Chirapu SR, Rotter CJ, Miller EL, Varma MV, Dow RL, Finn MG. High specificity in response of the sodium-dependent multivitamin transporter to derivatives of pantothenic acid. Curr Top Med Chem. 2013;13(7):837-842
      24. Tarr JB, Tamura T, Stokstad EL. Availability of vitamin B6 and pantothenate in an average American diet in man. Am J Clin Nutr. 1981 Jul;34(7):1328-37
      25. Leung LH. Pantothenic acid deficiency as the pathogenesis of acne vulgaris. Med Hypotheses. 1995 Jun;44(6):490-2
      26. Leung LH. A stone that kills two birds: how pantothenic acid unveils the mysteries of acne vulgaris and obesity. (1997) J Orthomol Med 12 (2):99-114.
      27. Abdelatif M, Yakoot M, Etmaan M. Safety and efficacy of a new honey ointment on diabetic foot ulcers: a prospective pilot study. J Wound Care. 2008 Mar;17(3):108-10.
      28. Celebi S, Tepe C, Yelken K, Celik O. Efficacy of dexpanthenol for pediatric post-tonsillectomy pain and wound healing. Ann Otol Rhinol Laryngol. 2013;122(7):464-467
      29. Miller JW, Rucker RB. Pantothenic acid. In: Erdman JWJ, Macdonald IA, Zeisel SH, eds. Present Knowledge in Nutrition. 10th ed. Ames: Wiley-Blackwell; 2012:375-390.
      30. Wiederholt T, Heise R, Skazik C, et al. Calcium pantothenate modulates gene expression in proliferating human dermal fibroblasts. Exp Dermatol. 2009;18(11):969-978
      31. Rumberger JA, Napolitano J, Azumano I, Kamiya T, Evans M. Pantethine, a derivative of vitamin B(5) used as a nutritional supplement, favorably alters low-density lipoprotein cholesterol metabolism in low- to moderate-cardiovascular risk North American subjects: a triple-blinded placebo and diet-controlled investigation. Nutr Res. 2011;31(8):608-61
      32. Evans M, Rumberger JA, Azumano I, Napolitano JJ, Citrolo D, Kamiya T. Pantethine, a derivative of vitamin B5, favorably alters total, LDL and non-HDL cholesterol in low to moderate cardiovascular risk subjects eligible for statin therapy: a triple-blinded placebo and diet-controlled investigation. Vasc Health Risk Manag. 2014 Feb 27;10:89-100.
      33. Scientific Opinion on Dietary Reference Values for pantothenic acid. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). European Food Safety Authority (EFSA), Parma, Italy. EFSA Journal 2014;12(2):3581
      34. Said, HM. Intestinal absorption of water-soluble vitamins in health and disease. Biochem J. 2011 Aug 1;437(3):357-72.
      35. Strickland KC, Hoeferlin LA, Oleinik NV, Krupenko NI, Krupenko SA. Acyl carrier protein-specific 4'-phosphopantetheinyl transferase activates 10-formyltetrahydrofolate dehydrogenase. J Biol Chem. 2010;285(3):1627-1633.

      Authored by Dr Peter Engel in 2010, reviewed and revised by Ines Warnke on 29.05.2017