News
Most women in the UK do not take folic acid before pregnancy
5 March 2014
A new UK study reports that less than one in three women take folic acid supplements before pregnancy to prevent birth defects.
31 May 2016
A study of rats fed either fructose or fructose with DHA for 6 weeks was conducted at the University of California (2). The fructose only animals exhibited impairment to memory and adverse blood profiles (raised glucose, triglycerides and insulin). However, the fructose + DHA group had the same memory and blood profile as the control group. These results suggest DHA may be protective against the adverse metabolic effects of fructose consumption.
At the end of 2012, a paediatric endocrinologist named Dr. Robert Lustig published a highly popular, though controversial, book called “Fat Chance: The bitter truth about sugar.” The theme of the book is the theory that fructose disrupts normal human metabolism, initiating metabolic syndrome and obesity (3). In a subsequent academic paper, Dr. Lustig provides evidence that fructose can have a similar effect to alcohol in the brain (4).
An article in the Sydney Herald reported on a study that appeared to indicate that the marine omega 3 fatty acid Docosahexaenoic Acid (DHA) could reverse impairment to memory caused by fructose consumption in laboratory rats (1). Previously, it had been shown that fructose-induced metabolic syndrome in rats reduced hippocampal-dependent memory (5). The new study (2) fed either fructose (15% in drinking water) or the same level of fructose but with 1.2% DHA to lab rats for 6 weeks. (The fructose level is comparable to consumption of between 1 to 2 litre of a regular soda beverage per day by a 60kg adult). At the end of 6 weeks, a range of metabolic tests were carried out and the rats were tested for memory retention by measuring their performance in a Barnes maze. Rats with impaired memory take longer to negotiate the maze. These results were compared to those of a control group of rats who consumed neither fructose or DHA.
As expected, the fructose only rats took longer to get through the maze than the other groups and had significantly increased levels of blood glucose, blood triglycerides, insulin and insulin index. Remarkably, the fructose + DHA group exhibited none of these negative effects and had approximately the same memory retention and metabolic measures as the control group.
These results suggest that DHA can counteract the negative epigenetic changes to metabolism caused by fructose consumption. However, it has yet to be shown if these effects would be translated could be translated to humans.
5 March 2014
A new UK study reports that less than one in three women take folic acid supplements before pregnancy to prevent birth defects.
1 December 2015
In 2000, the USA Institute of Medicine (IoM) noted that the amount of vitamin E necessary to maintain the correct metabolism of polyunsaturated fatty acids (PUFAs) in cell membranes is related to the intake of PUFAs. A recent review by Raederstorff et al. examines in detail the relationship between PUFA intake and vitamin E requirement. The basal metabolic requirement of 3 to 4 mg/day α-tocopherol needs to be increased to 12.5 to 20 mg/day, just to balance out typical intakes of PUFAs in the Western diet.
1 February 2013
According to new US research beta-carotene may lower the risk of type-2 diabetes in people with a common genetic variation, while vitamin E (gamma-tocopherol) may increase risk of developing the disease.