09 November 2009
High combined intakes of vitamin C and vitamin E, beta-carotene, lutein, and zeaxanthin from food may decrease the frequency of chromosome damage in ionizing radiation-exposed persons, a new study reports.
The study examined the association between the frequency of chromosome translocations, as a biomarker of cumulative DNA damage, and intakes of vitamins C and E and carotenoids in 82 male airline pilots (1). The results showed that high dietary antioxidant intakes were associated with a significant decrease in DNA damage induced by ionizing radiation (IR), a cause of cancer.
The intake of antioxidants, which can neutralize reactive oxygen species (ROS) generated endogenously or exogenously, has been extensively investigated in relation to DNA damage and cancer risk. Ionizing radiation (IR) is an established human cancer factor and an efficient inducer of chromosome abnormalities, which have also been shown to be associated with increased cancer risk in prospective studies. Airline pilots are exposed to elevated levels of cosmic IR.
During past decades, numerous animal or in vitro studies have suggested that antioxidants may provide protection against several forms of DNA damage induced by IR. To date, human data supporting these associations are limited. Of the dietary antioxidants, vitamins C and E and beta-carotene have been the focus of most research.
24 May 2013
A new study reports that blood vitamin D concentrations of people living in São Paulo, Brazil, are good among the young and active during the summer, but not so in the winter, and that the elderly have poor levels year round.
12 May 2014
A new US study reports that low blood vitamin D concentrations seem to be related to an increased chance of developing prostate cancer.
14 November 2016
