04 July 2013
A high-dose supplementation with vitamin D may be an easy adjunct therapy for depression and major cardiovascular risk factors among women with type 2 diabetes, reports a new US study.
The clinical pilot study included 46 women (average age of 55 years) who had suffered from type 2 diabetes for an average of 8 years and had insufficient blood concentrations of vitamin D (18 ng/ml), who took a weekly vitamin D dose of 50,000 international units for six months (1). The study results showed that the participants’ vitamin D concentrations reached sufficient levels (an average of 38 ng/ml) and their moods improved significantly: while a depression symptom survey indicated moderate depression at the beginning of the study, the survey results indicated no depression after six months. In addition, blood pressure im-proved, with the upper pressure decreasing from 140.4 mm Hg to 132.5 mm Hg.
The researchers commented that larger, randomized controlled trials are needed to determine the impact of vitamin D in diabetes patients. About 10 percent of the people in the United States have diabetes, and the incidence is projected to increase to 25 percent by 2050. Women with type 2 diabetes have worse disease progression than men, which may be due to depression, a malady that affects more than 25 percent of women with diabetes. Depression impairs a patient’s ability to manage her disease by eating right, exerci-sing, taking medications, etc. Many Americans do not get enough vitamin D (the recommended dietary allowance for women 51 to 70 is 600 IU per day) and people with diabetes are at especially high risk for vitamin D insufficiency or deficiency because of limited intake of foods high in vitamin D, obesity, lack of sun exposure and genetic variations.
6 October 2016
In a new study, a group of low to middle income mothers (n=1,094) in Cuernavaca, Mexico who were supplemented with 400 mg of algal DHA omega-3 during the last half of pregnancy had children with higher scores on a test of cognitive function that measured sustained attention.
20 January 2014
New studies from Sweden report that low intakes and low serum concentrations of vitamin E seem to be associated with an increased rate of fracture in older women and men.
15 January 2014
Vitamin B12 is a key nutrient associated with one-carbon metabolic pathways related to substrate metabolism, synthesis, stability of nucleic acids and methylation of DNA which regulates gene expression.
