Topic of the Month
1 June 2012
The globally rising need for and use of medicines continues unabated. In the context of an ever widening range of medicinal therapies and a constantly growing number of pharmaceutical substances, interactions between bioactive substances are very significant. In the past, interactions between drugs and micronutrients received little attention in pharmaceutical and medical practice, but now medication-induced disturbances of micronutrient status are leading to a number of undesirable pharmacological effects. More-over, concomitant food intake can reinforce or diminish the bioavailability and effect of a pharmaceutical substance. In some cases, synergistic effects can arise from interactions between pharmaceuticals and micronutrients: micronutrients may complement medicinal treatment and enhance its effectiveness or reduce potential side-effects.