Low levels of vitamin B6 may increase the risk of cardiovascular disease, says a new study.
The study with 1,205 people found that higher levels of pyridoxal-5'-phosphate (PLP), the active form of vitamin B6, were linked to lower levels of C-reactive protein (CRP), a marker of inflammation, as well as lower levels of 8-OHdG, a marker for oxidative stress, both of which are related to heart disease risk (1).
CRP is produced in the liver and is a known marker for inflammation. Increased levels of CRP are a good predictor for the onset of both type-2 diabetes and cardiovascular disease.
Vitamin B6 may influence cardiovascular disease risk through mechanisms other than the reduction of the amino acid homocysteine, the researchers commented.