News
Insufficient vitamin E intakes may increase hip fracture risk
1 September 2014
According to a new study from Norway, older people with low blood vitamin E concentrations seem to have an increased risk of developing hip fracture.
05 November 2013
Variations in genes involved in responses to oxidative stress may be crucial for beneficial effects of vitamin E in reducing inflammation, suggests a new study from the UK.
To explore the role of genetic variants (polymorphisms) on changes in inflammatory cytokine production after vitamin E (alpha-tocopherol) supplementation, inflammatory markers (TNF-alpha and IL-1beta, -6, and -10) were measured in blood samples of 160 healthy, middle-aged male volunteers at the beginning of the study and after 6 weeks of supplementation with 75 IU or 600 IU alpha-tocopherol per day (1). The study results showed that the ability of alpha-tocopherol to decrease inflammatory marker concentrations depended on several variations in the participants’ genes involved in inflammation or responses to oxidative stress.
The researchers concluded that the effect of vitamin E supplementation on the production of inflammatory cytokines appears to be dependent on an individual’s genotype. These genotype-specific differences may help explain some of the discordant results in studies that have used vitamin E. Despite evidence of antioxidant effects of vitamin E in vitro and in animal studies, large, randomized clinical trials have not substantiated a benefit of vitamin E in reducing inflammation in humans. Thus, an individual’s genetic background may affect the response to alpha-tocopherol supplementation.
1 September 2014
According to a new study from Norway, older people with low blood vitamin E concentrations seem to have an increased risk of developing hip fracture.
20 September 2013
New research from Norway reports that supplements containing vitamin D3 can increase blood concentrations more effectively than the D2 form.
27 March 2013
A new US study reports that regular vitamin D supplementation may help African-Americans lower their blood pressure.