The Joint Food and Agricultural Organization (FAO)/World Health Organization (WHO) Expert Committee on Food Additives (JECFA) assessed the safety of FloraGLO® Lutein for use in foods in June of 2004. Based upon their review, JECFA established an Acceptable Daily Intake (ADI) for lutein and zeaxanthin from marigolds at 2 mg/kg body weight/day (i.e.140 mg/day for a person weighing 154 pounds). This amount is considerably higher than the amounts commonly recommended for the daily intake in vitamin/dietary supplement products sold in the market.
Additionally, the European Food Safety Authority (EFSA) confirmed the safety of lutein using a more conservative ADI of 1 mg/kg body weight/day while simultaneously confirming the safety of lutein for nutritional uses by infants and young children in 2006.
There is no reason to limit the consumption of carotenoid-rich fruits and vegetables during pregnancy (26).
Presently, no tolerable upper intake level (UL) has been set for lutein and zeaxanthin.
There are no well-known drug interactions with lutein or zeaxanthin.
Authored by Dr Peter Engel in 2010, reviewed and revised by Jonas Wittwer on 13.06.2017