BETACAROTENO

Bibliografía

BIBLIOGRAFÍA

  1. Institute of Medicine, Food and Nutrition Board. Beta-carotene and other carotenoids. Dietary reference intakes for vitamin C, vitamin E, selenium, and carotenoids. Washington, D.C.: National Academy Press; 2000:325–400.
  2. Pavia SA, Russell RM. Beta-carotene and other carotenoids as antioxidants. J Am Coll Nutr 1999; 18:426–33.
  3. Young AJ, Lowe GM. Antioxidant and prooxidant properties of carotenoids. Arch Biochem Biophys. 2001; 385(1):20–27.
  4. Bertram JS. Carotenoids and gene regulation. Nutr Rev. 1999;57(6):182–191.
  5. Stahl W, Nicolai S, Briviba K, et al. Biological activities of natural and synthetic carotenoids: induction of gap junctional communication and singlet oxygen quenching. Carcinogenesis. 1997; 18(1):89–92.
  6. van Poppel G, Spanhaak S, Ockhuizen T. Effect of beta-carotene on immunological indexes in healthy male smokers. Am J Clin Nutr. 1993; 57(3):402–407.
  7. Hughes DA, Wright AJ, Finglas PM, et al. The effect of beta-carotene supplementation on the immune function of blood monocytes from healthy male nonsmokers. J Lab Clin Med. 1997; 129(3):309–317.
  8. Santos MS, Gaziano JM, Leka LS, Beharka AA, Hennekens CH, Meydani SN. Beta-carotene-induced enhancement of natural killer cell activity in elderly men: an investigation of the role of cytokines. Am J Clin Nutr. 1998; 68(1):164–170.
  9. Peto R, Doll R, Buckley JD, Sporn MB. Can dietary beta-carotene materially reduce human cancer rates? Nature. 1981; 290(5803):201-208.
  10. Ziegler RG. A review of epidemiologic evidence that carotenoids reduce the risk of cancer. J Nutr. 1989; 119(1):116–122.
  11. Michaud DS, Feskanich D, Rimm EB, et al. Intake of specific carotenoids and risk of lung cancer in 2 prospective US cohorts. Am J Clin Nutr. 2000; 72(4):990–997.
  12. Mannisto S, Smith-Warner SA, Spiegelman D, et al. Dietary Carotenoids and Risk of Lung Cancer in a Pooled Analysis of Seven Cohort Studies. Cancer Epidemiol Biomarkers Prev. 2004; 13(1):40–48.
  13. Gallicchio L, Boyd K, Matanoski G, et al. Carotenoids and the risk of developing lung cancer: a systematic review. Am J Clin Nutr. 2008; 88(2):372–383.
  14. Rissanen TH, Voutilainen S, Nyyssonen K, Salonen R, Kaplan GA, Salonen JT. Serum lycopene concentrations and carotid atherosclerosis: the Kuopio Ischaemic Heart Disease Risk Factor Study. Am J Clin Nutr. 2003; 77(1):133–138.
  15. Dwyer JH, Paul-Labrador MJ, Fan J, Shircore AM, Merz CN, Dwyer KM. Progression of Carotid Intima-Media Thickness and Plasma Antioxidants: The Los Angeles Atherosclerosis Study. Arterioscler Thromb Vasc Biol. 2003.
  16. McQuillan BM, Hung J, Beilby JP, Nidorf M, Thompson PL. Antioxidant vitamins and the risk of carotid atherosclerosis. The Perth Carotid Ultrasound Disease Assessment study (CUDAS). J Am Coll Cardiol. 2001; 38(7):1788–1794.
  17. Rissanen T, Voutilainen S, Nyyssonen K, Salonen R, Salonen JT. Low plasma lycopene concentration is associated with increased intima-media thickness of the carotid artery wall. Arterioscler Thromb Vasc Biol. 2000; 20(12):2677–2681.
  18. D'Odorico A, Martines D, Kiechl S, et al. High plasma levels of alpha- and beta-carotene are associated with a lower risk of atherosclerosis: results from the Bruneck study. Atherosclerosis. 2000; 153(1):231–239.
  19. Iribarren C, Folsom AR, Jacobs DR, Jr., Gross MD, Belcher JD, Eckfeldt JH. Association of serum vitamin levels, LDL susceptibility to oxidation, and autoantibodies against MDA-LDL with carotid atherosclerosis. A case-control study. The ARIC Study Investigators. Atherosclerosis Risk in Communities. Arterioscler Thromb Vasc Biol. 1997; 17(6):1171–1177.
  20. Sesso HD, Buring JE, Norkus EP, Gaziano JM. Plasma lycopene, other carotenoids, and retinol and the risk of cardiovascular disease in women. Am J Clin Nutr. 2004; 79(1):47–53.
  21. Rissanen TH, Voutilainen S, Nyyssonen K, et al. Low serum lycopene concentration is associated with an excess incidence of acute coronary events and stroke: the Kuopio Ischaemic Heart Disease Risk Factor Study. Br J Nutr. 2001; 85(6):749–754.
  22. Street DA, Comstock GW, Salkeld RM, Schuep W, Klag MJ. Serum antioxidants and myocardial infarction. Are low levels of carotenoids and alpha-tocopherol risk factors for myocardial infarction? Circulation. 1994; 90(3):1154–1161.
  23. Ito Y, Kurata M, Suzuki K, Hamajima N, Hishida H, Aoki K. Cardiovascular disease mortality and serum carotenoid levels: a Japanese population-based follow-up study. J Epidemiol. 2006; 16(4):154–160.
  24. Buijsse B, Feskens EJ, Kwape L, Kok FJ, Kromhout D. Both alpha- and beta-carotene, but not tocopherols and vitamin C, are inversely related to 15-year cardiovascular mortality in Dutch elderly men. J Nutr. 2008; 138(2):344–350.
  25. Sesso HD, Buring JE, Norkus EP, Gaziano JM. Plasma lycopene, other carotenoids, and retinol and the risk of cardiovascular disease in men. Am J Clin Nutr. 2005; 81(5):990–997.
  26. Hak AE, Stampfer MJ, Campos H, et al. Plasma carotenoids and tocopherols and risk of myocardial infarction in a low-risk population of US male physicians. Circulation. 2003; 108(7):802–807.
  27. Evans RW, Shaten BJ, Day BW, Kuller LH. Prospective association between lipid soluble antioxidants and coronary heart disease in men. The Multiple Risk Factor Intervention Trial. Am J Epidemiol. 1998; 147(2):180–186.
  28. Sahyoun NR, Jacques PF, Russell RM. Carotenoids, vitamins C and E, and mortality in an elderly population. Am J Epidemiol. 1996; 144(5):501–511.
  29. The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. N Engl J Med. 1994; 330(15):1029–1035.
  30. Hennekens CH, Buring JE, Manson JE, et al. Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease. N Engl J Med. 1996; 334(18):1145–1149.
  31. Greenberg ER, Baron JA, Karagas MR, et al. Mortality associated with low plasma concentration of beta carotene and the effect of oral supplementation. JAMA. 1996; 275(9):699–703.
  32. Omenn GS, Goodman GE, Thornquist MD, et al. Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. N Engl J Med. 1996; 334(18):1150–1155.
  33. Köpcke W and Krutmann J (2008) Protection from sunburn with beta-Carotene--a meta-analysis. Photochemistry and Photobiology 84(2):284–8.
  34. Christen WG, Manson JE, Glynn RJ, et al. A randomized trial of beta carotene and age-related cataract in US physicians. Arch Ophthalmol. 2003; 121(3):372–378.
  35. Chylack LT, Jr., Brown NP, Bron A, et al. The Roche European American Cataract Trial (REACT): a randomized clinical trial to investigate the efficacy of an oral antioxidant micronutrient mixture to slow progression of age-related cataract. Ophthalmic Epidemiol. 2002; 9(1):49–80.
  36. Gritz DC, Srinivasan M, Smith SD, et al. The Antioxidants in Prevention of Cataracts Study: effects of antioxidant supplements on cataract progression in South India. Br J Ophthalmol. 2006; 90(7):847–851.
  37. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E and beta carotene for age-related cataract and vision loss: AREDS report no. 9. Arch Ophthalmol. 2001; 119(10):1439–1452.
  38. Mathews-Roth MM. Carotenoid functions in photoprotection and cancer prevention. J Environ Pathol Toxicol Oncol. Jul-Oct 1990; 10(4-5):181–92.
  39. European Food Safety Authority, Scientific Committee on Food. Tolerable Upper Intake Levels for Vitamins and Minerals. 2006: ISBN: 92-9199-014-0.
  40. Biesalski HK. et al. Antioxidant vitamins in prevention. Clin Nutr. 1997; 16:151–155.
  41. Elmadfa I. et al.,European Nutrition and Health Report 2004. Forum Nutr. Basel: Karger; 2005.
  42. Pelz R et al. (1998) Carotenoid intake in the German National Food Consumption Survey. Z Ernaehrungswiss. 37: 319–27
  43. Adolf T et al. (1995) Ergebnisse der Nationalen Verzehrsstudie (1985-1988) über die Lebensmittel- und Nährstoffaufnahme in der Bundesrepublik Deutschland. In: VERA-Schriftenreihe, Band XI. W Kübler, HJ Anders, W Heeschen (Hrsg.) Wissenschaftlicher Fachverlag Dr. Fleck, Niederkleen.
  44. Nationale Verzehrsstudie II, 2008 (www.was-esse-ich.de), Max-Rubner-Institut, Karlsruhe, Germany.
  45. Scientific Committee on Food (2000) Opinion of the Scientific Committee on Food on the safety of use of beta carotene from all dietary sources; SCF/CS/ADD/COL/159 Final.
  46. Scientific Committee on Food (2000) Opinion of the Scientific Committee on Food on the Tolerable Upper Intake Level of Beta Carotene; SCF/CS/NUT/UPPLEV/37 Final
  47. Beitz R., Mensink GBM, Rams S, Döring A, (2004): Vitamin- und Mineralstoffsupplementierung in Deutschland. Bundesgesundheitsblatt 47:1057–1065.
  48. Jalal F, Nesheim MC, Agus Z, Sanjur D, Habicht JP. Serum retinol concentrations in children are affected by food sources of beta-carotene, fat intake, and anthelmintic drug treatment. Am J Clin Nutr. 1998; 68(3):623–629.
  49. van Het Hof KH, West CE, Weststrate JA, Hautvast JG. Dietary factors that affect the bioavailability of carotenoids. J Nutr. 2000; 130(3):503–506.
  50. During A, Harrison EH. Intestinal absorption and metabolism of carotenoids: insights from cell culture. Arch Biochem Biophys. 2004; 430(1):77–88.
  51. Omenn GS, Goodman GE, Thornquist MD, et al. Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial. J Natl Cancer Inst. 1996; 88(21):1550–1559.
  52. Lee I-M, Cook NR, Manson JE, Buring JE, Hennekens CH: Beta-carotene supplementation and incidence of cancer and cardiovascular disease: the Womens´ Health Study. J Natl Cancer Inst. 1999; 91: 2102–2109.
  53. Vainio H, Rautalahti M. An international evaluation of the cancer preventive potential of carotenoids. Cancer Epidemiol Biomarkers Prev. 1998; 7(8):725–728.
  54. U.S. Preventive Services Task Force. Routine vitamin supplementation to prevent cancer and cardiovascular disease: recommendations and rationale. Ann Intern Med. 2003; 139(1):51–55.
  55. Bjelakovic G, Nikolova D, Gluud LL, et al. Mortality in Randomized Trials of Antioxidant Supplements for Primary and Secondary Prevention - A Systematic Review and Meta-analysis. JAMA 2007; 297:842–857.
  56. Satia, Jessie A et al: Long-term Use of β-Carotene, Retinol, Lycopene, and Lutein Supplements and Lung Cancer Risk: Results From the VITamins And Lifestyle (VITAL)
    y, Am J Epidemiol. 2009; 169(7):815–828.
  57. Hercberg S, Ezzedine K, Guinot C; et al. Antioxidant supplementation increases the risk of skin cancers in women but not in men. J Nutr. 2007; 137(9):2098–2105.
  58. Green AC et al. Antioxidant supplementation and risk of skin cancers. J Nutr. 2008; 138(5):978.
  59. Asgari M. M. et al. Antioxidant Supplementation and Risk of Incident Melanomas - Results of a Large Prospective Cohort Study. Arch Dermatol, 2009; 145(8):879–882.
  60. Goralczyk R. Beta-Carotene and Lung Cancer in Smokers: Review of Hypotheses and Status of Research. Nutrition and Cancer. 2009; 61(6):767 — 774.
  61. Biesalski H. K. et al. Reexamination of a meta-analysis of the effect of antioxidant supplementation on mortality and health in randomized trials. Nutrients. 2010; 2:929–949.
  62. EFSA Panel on Food Additives and Nutrient Sources added to Food. Statement on the safety of beta-carotene use in heavy smokers. EFSA Journal 2012; 10(12):2953.
  63. Bjelakovic G. et al. Meta-Regression Analyses, Meta-Analyses, and Trial Sequential Analyses of the Effects of Supplementation with Beta-Carotene, Vitamin A, and Vitamin E Singly or in Different Combinations on All-Cause Mortality: Do We Have Evidence for Lack of Harm?  PLoS One. 2013; 8(9):e74558.