Funciones para la salud

Living organisms extract most of their energy from  oxidation-reduction  (redox) reactions, which involve the transfer of electrons. Vitamin B2 (riboflavin) is the precursor of 'flavocoenzymes' that participate in  redox reactions  by various metabolic pathways  (3) , support the  metabolization  of drugs and toxins  (4)  and are essential for the  metabolism  of carbohydrates, fats and proteins. 

The flavoenzyme-dependent 'glutathione redox cycle' plays an important antioxidant role  , protecting the body against reactive oxygen species   that can have harmful effects. Riboflavin deficiency has been associated with increased  oxidative stress  (4) . Another oxidation reaction dependent on flavoenzymes generates uric acid, one of the most effective water-soluble oxidants present in the blood  (5) .

Flavoproteins are involved in the metabolism of other vitamins of the vitamin B complex such as vitamins  B3 ,  B6  and  B9  (6,  7,  8) . 

Although the mechanism is unclear, animal research suggests that vitamin B2 (riboflavin) deficiency may impede  iron absorption  , increase intestinal iron loss, or prevent the use of iron for hemoglobin synthesis. In humans, improving the nutritional status of riboflavin has been shown to increase the level of circulating hemoglobin  (9) .

The  European Food Safety Authority  (EFSA) , which provides scientific advice to policy makers, has confirmed that clear health benefits have been demonstrated from dietary vitamin B2 intake, as it contributes to the following:

  • Normal functioning   of the energy-producing metabolism ;
  • Normal functioning of iron metabolism in the body;
  • Maintenance of  normal skin and  mucous membranes;
  • Maintenance of normal red blood cells;
  • Preservation of normal vision ;
  • Protection of cell constituents against oxidative damage  ;
  • Maintenance of the normal functioning of the nervous system;
  • Reduction of tiredness and fatigue.